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Pharma giant Roche does deal to develop superbug killer

Pharmaceuticals giant Roche said on Monday that it had joined forces with fellow Swiss company Polyphor to develop an antibiotic to fight a superbug that has taken hold in hospitals.

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Bacterium infecting cystic fibrosis patients genetically evolves to live in...

The bacterium that's the most important pathogen in patients with cystic fibrosis (CF) has genetically evolved and adapted to survive in CF-infected lungs and evade antibiotic treatments, scientists...

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Bacterial food web may be key to cystic fibrosis

(Medical Xpress)—Cystic fibrosis patients suffer from chronic bacterial infections and thick mucous in their lungs, due largely to a combination of microbial infections and resulting inflammation. A...

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Scientists uncover potential new defence against hospital-acquired infections

(Medical Xpress)—Infection specialists have uncovered new evidence about how the human body's immune system responds to invading germs – a finding which could help combat hospital-acquired infections...

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New rapid diagnosis for antibiotic resistance

A rapid diagnostic test for multi-resistance to broad-spectrum antibiotics has just been developed at the University of Fribourg. Prof Patrice Nordmann and Dr Laurent Poirel of the Medical and...

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Highly drug resistant, virulent strain of Pseudomonas aeruginosa arises in Ohio

A team of clinician researchers has discovered a highly virulent, multidrug resistant form of the pathogen, Pseudomonas aeruginosa, in patient samples in Ohio. Their investigation suggests that the...

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Hospital superbugs breakthrough: Antibacterial gel kills them using natural...

Scientists at Queen's University Belfast have made a breakthrough in the fight against the most resistant hospital superbugs.

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Researchers find ionic liquids able to safely penetrate both skin and...

(Medical Xpress)—A team of medical researchers from several institutions in the U.S. has found that some ionic liquids are able to safely penetrate both skin and bacterial biofilms, opening the door to...

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Researchers uncover hidden infection route of major bacterial pathogen

Researchers at the University of Liverpool's Institute of Infection and Global Health have discovered the pattern of infection of the bacterium responsible for causing severe lung infections in people...

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New drug formulations to boost fight against respiratory illnesses and...

A team of five researchers and clinicians in Singapore led by Dr Desmond Heng, ICES, has developed a new combination of drugs to effectively combat bacteria in the lungs which lead to common...

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Researchers find novel way body defends against harmful bacteria

Bacterial infections can cause major problems for people undergoing treatment for cancer and other diseases. The concern is especially acute during hospitalization, when patients often have weakened...

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Drug proves effective against antibiotic-resistant 'superbugs'

A treatment pioneered at the University of Pittsburgh Center for Vaccine Research (CVR) is far more effective than traditional antibiotics at inhibiting the growth of drug-resistant bacteria, including...

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Research could be life-prolonging for cystic fibrosis patients

Preventing lung infections in childhood could stop later life-threatening infections for people with cystic fibrosis (CF), according to the latest research carried out at Aston University.

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New cystic fibrosis research takes aim at deadly pathogen

A new method of testing the most common cause of life-threatening infection in people with cystic fibrosis could improve efforts to study and combat the illness.

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Whole genome sequencing found to rapidly enhance infection control

Whole genome sequencing can quickly isolate the specific strain of bacteria causing an outbreak, identify the source of contamination, and enable rapid infection prevention to stop the spread of...

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A heavy metal balancing act: Studying copper to help cells battle bacterial...

Copper is an essential micronutrient that all organisms need to maintain healthy metabolism. But unless it is bound to proteins, copper is also toxic to cells. With a $1.3 million award from the...

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Evolving insights into cystic fibrosis lung infections

Recent research progress into how bacteria adapt and evolve during chronic lung infections in cystic fibrosis patients could lead to better treatment strategies being developed, according to a new...

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Newborn screening for cystic fibrosis

A new study led by a team from the Research Institute of the McGill University Health Centre (RI-MUHC) and Cystic Fibrosis Canada reinforces the benefits of newborn screening for cystic fibrosis (CF)...

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DNA-modulating drug attenuates lung inflammation in mice

Patients with cystic fibrosis (CF) suffer from chronic respiratory infections, primarily caused by Pseudomonas aeruginosa, which lead to airway inflammation and damage. Several recent studies have...

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Antimicrobial resistance to carbapenems increasing

(HealthDay)—Antimicrobial resistance to carbapenems has increased, and consumption of antibiotics, especially carbapenems, is associated with antimicrobial resistance of Pseudomonas aeruginosa,...

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